A–Z index

Bioactivity

At a glance: A measurable effect a chemical has on cells, tissues, or living organisms.

Biological activity refers to the impacts from contact with a molecule that affect metabolic or physiological reactions. 11 In high-throughput assays it is quantified by the AC50 — the concentration required to elicit 50% of maximal activity. 12 Important nuance: perturbations observed in in vitro assays are not indicative on their own of an adverse health effect. 12 Bioactivity is a signal used within NGRA, not proof of harm.

Sources

  1. Biological Activity — an overview
  2. Government of Canada: Bioactivity exposure ratio in priority setting and risk assessment
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